Linkage Group Selection: Towards Identifying Genes Controlling Strain Specific Protective Immunity in Malaria
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Linkage Group Selection: Towards Identifying Genes Controlling Strain Specific Protective Immunity in Malaria
Protective immunity against blood infections of malaria is partly specific to the genotype, or strain, of the parasites. The target antigens of Strain Specific Protective Immunity are expected, therefore, to be antigenically and genetically distinct in different lines of parasite. Here we describe the use of a genetic approach, Linkage Group Selection, to locate the target(s) of Strain Specific...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2007
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0000857